M.Sc. Veterinary Pathology

Department of Veterinary Pathology

Master of Science in Veterinary Pathology

M.Sc. Veterinary Pathology

List of Academic Staff

Name	Status and Qualification	Research Interest
M. Adam	Senior    Lecturer    & Acting Head of Department DVM,M.Sc.,Ph.D.(ABU,Zaria)	Anatomical Pathology, Infectious Disease Pathology
B.O.Akanbi	Reader DVM,M.V.Sc.,Ph.D.(Ibadan);Cert. Vet. Diag. Path. (Vom); FCVSN (Abuja)	Veterinary  Anatomic Pathology, Viral Infectious Diseases Pathology
Jamila A. Atata	Senior Lecturer DVM,M.Sc.,Ph.D.(ABU,Zaria)	Zoonotic Neglected Tropical Diseases (Ntds), Clinical Pathology, Immuno- Oncology,  Molecular Diagnostics.
A. AAjadi	Lecturer I DVM(Ibadan);M.Sc.(Selangor)	Fish Pathology, Clinical Pathology, Molecular Diagnostics.
*S. O. Salami	Professor DVM,M.Sc.,Ph.D.(ABU,Zaria)	Veterinary Gross Anatomy, Embryology
*S.F.Ambali	Professor DVM,M.Sc.,Ph.D.(ABU,Zaria)	Neuropharmacology, Environmental Toxicology, Ethnopharmacology
*B.O.Okediran	Senior Lecturer B.Sc.(OAU,Ile-Ife);DVM(Ibadan); M.Sc., Ph.D. (UNAAB, Abeokuta)	Veterinary Biochemistry, Clinical Pathology

Introduction

The M.Sc. Veterinary Pathology programme is intended to train Doctor of Veterinary Medicine (DVM) graduates in advanced veterinary diseases pathology and diagnosis; and to carry out diagnostic and investigative research in three research tracks of Diagnostic Pathology, Clinical Pathology and Avian Pathology for the award of the M.Sc. in Veterinary Pathology. The programme will equip students for employment in livestock production, academia, biomedical and biopharmaceutical industry.

Philosophy

The philosophy of the program is the provision of advanced level postgraduate training in the pathology of domestic, wildlife, poultry, aquatic and laboratory animals usually kept for livestock production, in zoological gardens, aquatic industry and for biomedical and biopharmaceutical research.

Aim and Objectives

The programme is aimed at providing in-depth research skills in the area of Veterinary Pathology.

The objective for the M.Sc.degree programme is to:

Produce veterinary pathologists required in academia, research institutes and in biomedical and biopharmaceutical industries.

Admission Requirements

The admission requirements into the programme will be as follows:

O‘ level credit in five subjects including Mathematics, Biology, Physics, Chemistry and English Language and Doctor of Veterinary Medicine(DVM)degree or its equivalent from a recognised institution.

Duration of the Programme

The Full-time programme shall run for a minimum of 18 calendar months and a maximum of 24 calendar months.

The part-time programme shall run for a minimum of 24 calendar months and a maximum of 36 calendar months

Detailed Course Description

VTC 813 Biomedical Research Methodology and Communication   2 Credits

History and legal basis of research ethic. Ethical requirements. Ethical review procedure. Ethical issues and requirements: data protection, privacy, informed consent, research on animals and humans, dual use. Identifying research fields. Identifying funding resources. Developing a grant proposal: basic components of a grant proposal, budget and budgeting, research planning and design. Writing research protocol. Submitting a research proposal. Implementing the research project. Describing and analysing research results. Interpreting research results. Report writing. Management control in biomedical research. Challenges and opportunities in collaborative scientific research. Research communication: communicating to scientists, funding agencies, health professionals, policy makers, patients/clients, the community, and public media. Writing scientific papers. Publishing scientific papers. Making a scientific presentation.30h (T);C

VPH815 Biostatistics     2Credits

Statistics, study designs, scales of measurement, quality of measurement, statistical variable/data, qualitative and quantitative data sources. Sampling and sample size determination, Data organisation: Statistics charts, tables, graphs frequency tables, frequency distribution; histogram, stem and leaf plot, box plot; summary indices: mean, median, modes; variance standard deviation; probability distributions: Normal, binomial, poisson distribution, descriptive statistics, frequency table, tables for qualitative and quantitative data, diagrams, types of diagrams. Data summarisation: Summary indices, measures of central tendency and dispersion; test of statistical hypothesis; confidence intervals; parametric and non-parametric tests: Z-test for proportions, Chi-square test, Fischer‘s exact test and T-test. Analysis of variance, regression and correlation, spearman rank and kendal correlation.15h(T);45h (P);C

VPH817 Bioinformatics   2Credits

Application of Bioinformatics in Veterinary Medicine, Bio-informatics software and data manipulation, GenBank, Nucleic acid amplification and sequencing, use of Gene Sequences Analysis software (Bio Edit®, MEGA, CLC), Phylogenetic tree construction and analysis.15h(T);45h (P);C

VPA801 Correlative Pathology   3 credits

Independent conduct of necropsy, histopathological and clinicopathological case analysis and presentation in the form of seminars and/ or discussion. Post-mortem cases will be derived from the departmental and the Veterinary Teaching Hospital (VTH) necropsy unit caseloads. Students will be expected to be on rotation at the post-mortem facilities at the department and the VTH and submit 25 cases during the duration of the programme for assessment. The species groups shall include small and domestic animals, laboratory animals, non-human primates and other animals used for biomedical research and drug safety assessment, birds, fish, zoo and wild animals.30h(T);45h (P);C

VPA802 Cellular Pathology and Carcinogenesis   2Credits

Mechanism of disease: cells and tissues to injury, degenerative, inflammatory, neoplastic. Biology of neoplastic cell; theories of oncogenesis. Disease processes; immune-pathology, tissue repair, neoplastic transformation.30h(T);C

VPA 803 Advanced Systemic Pathology I    3 Credits

Cardiovascular system diseases pathogenesis and pathology, respiratory system diseases pathogenesis and pathology, nervous system diseases pathogenesis and pathology, alimentary system diseases pathogenesis and pathology, pancreatic diseases pathogenesis and pathology, liver and biliary system diseases pathogenesis and pathology.30h(T);45h (P);C

VPA804 Advanced Systemic Pathology II    3 Credits

Basic reactions of the Skin and appendages. Pathogenesis and pathology of skin and appendages. Special senses (Eye and ear) disease pathogenesis and pathology. Musculoskeletal systems diseases pathogenesis and pathology.30h(T);45h (P);C

VPA805 Advanced Systemic Pathology III   3Credits

Basic reactions of the haematopoietic systems. Urinary system disease pathogenesis and pathology. Male reproductive system pathogenesis and pathology. Female reproductive system diseases pathogenesis and pathology. Endocrine system diseases pathogenesis and pathology. 30h(T); 45h(P); C

VPA806 Advanced Immunopathology   2Credits

Immune system diseases: including deficiencies, diseases of immunity. Hypersensitivity reactions: haemolytic diseases of new born, pemphigus diseases, drug reactions and autoimmune diseases. Experimental animal models of autoimmune diseases, cytokine and monoclonal antibody-based therapy and immunodeficiency diseases in animals.15h(T);45h (P);C

VPA807 Wildlife Pathology   2Credits

Viral diseases pathogenesis and pathology. Bacterial diseases pathogenesis and pathology. Protozoan diseases pathogenesis and pathology. Nutritional diseases of the zoo and wild animals: including Elephants and other mega vertebrates, small mammals including Marsupials, Wild Hoofed Deer, Reptiles, Amphibians, Non-human Primates and Marine mammals. Prevalent diseases in Nigerian zoos and wildlife parks.15h(T);45h (P);E

VPA808 Pathology of Laboratory Animals Diseases   2Credits

Infectious and non-infectious diseases of laboratory rodents: including Rats and Mice. Pathology of Genetically Engineered Mice: including knockout/knock-in, transgenic mice. Use of laboratory animals in biomedical and biopharmaceutical research.15h(T);45h (P);E

VPA 809 Advanced Avian Pathology   2 Credits

Examination and interpretation of naturally and experimentally induced lesions in avian species: including diagnosis of poultry diseases; viral, bacterial, parasitic, fungi, toxic and nutritional deficiency diseases.30h(T);45h (P);C

VPA 810 Advanced Aquatic Animal Pathology    3 Credits

Examination and interpretation of naturally and experimentally induced lesions in aquatic animal species: including the pathology of farmed fish diseases; including viral, bacterial, parasitic, fungi, toxic and nutritional deficiency.30h(T);45h (P);E

VPA811 Toxicological Pathology   2Credits

Gross and histopathology of toxic substances in organs and tissues. Survival curves. Organ weight tables. Clinical pathology parameters. Description and Interpretation of macro and/or microscopic incidence tables. Haematology and clinical chemistry and/or anatomic pathology findings interpretation in laboratory animals: to include comparing treated and non-treated groups. Format and methodology of toxicological pathology data. Conclusions or hypotheses regarding the safety of the test article. Dose-dependency of effects. Putative mechanism of action; including additional refinements of study protocols.15h(T);45h(P);E

VPA 812 Ultra-structural Pathology     2 Credits

Ultrastructural Pathology of domestic animal diseases: collection and preservation of tissues for electron microscopy. Processes in the production of micrographs. Interpretation of micrographs. Identification and diagnosis of cell and matrix components. Identification of cell types; including changes in injured cells, neoplastic cells, viral, bacterial and intracellular protozoan infections.15h(T); 45h (P); E

VPA813 Exfoliative Cytology   3Credits

Cytological examination of exfoliated cells of the skin; body cavity effusions and lymphatic tissue. Minimal animal body invasion as a diagnostic tool for disease and malignancy. Specimen collection, preservation, examination and interpretation.30h(T);45h (P);C

VPA814 Advanced Veterinary Haematology   3Credits

Bone marrow function. Evaluation of erythrocyte, leucocyte and platelet structure. Function and pathology: anaemia, pigment and iron metabolism, normal and defective blood coagulation. 30h(T); 45h (P); C

VPA815 Advanced Veterinary Clinical Biochemistry  3Credits

Evaluation of carbohydrates, lipids, protein, mineral and vitamin metabolism in health and disease. Function test: kidney, liver, pancreatic and thyroid function tests. Vitamins.30h(T);45h (P);C

VPA816 Diagnostic Methods in Veterinary Pathology    3Credits

Analysis of scientific studies. Basic molecular pathology. Pathology data description. Analysis and interpretation of pathology data. Use of basic principles and applied techniques in veterinary pathology; DNA PCR, Southern Blotting; RNA quantitative RT-PCR, Northern Blotting; Proteins Western Blotting; Tissue microarrays; Immunohistochemistry; immunofluorescence; ELISA; epigenetic alterations: DNA methylation, modifications of histones. Genetic modifications: transfection of cells, over-expression of genes, RNA interference, inducible expression, targeting of genes in mice and reporter assays: luciferase assays. Tissue Microarray (TMA). In-situ hybridization. Flow cytometry.30h(T);45h (P);C

VPA 817 Nutritional Pathology    2 Credits

Macroscopic and microscopic study of metabolic diseases of bone: protein; mineral and vitamin deficiencies. Disease processes induced by faulty nutrition.30h(T);C

VPA818 Advanced Pathology of Tropical Diseases of Domestic Animals 2Credits

Viral, bacterial, parasitic, mycotic and nutritional diseases of domestic animals in the tropics. 30h(T); C

VPA819 Seminar I   1Credit

Oral presentation of proposal and literature survey to be assessed by a panel of examiners during an oral presentation.45h(P);C

VPA820 Seminar II  1Credit

Oral presentation of research findings to be assessed by a panel of examiners during an oral presentation.45h(P);C

VPA899 Dissertation    6Credits

Original investigation into an approved problem in veterinary pathology under the supervision of an approved academic supervisor(s).270h(P);C

Graduation Requirements

A candidate must pass a minimum of 33 Credits made up of the following to be awarded the Master of Science degree in Veterinary Pathology

Core                                                                                                      31 Credits

Elective                                                                                                 2 Credits

Total                                                                                                      33Credits

Summary

Diagnostic Veterinary Pathology Option

Core courses:VTC813(2),VPH815(2),VPH817(2),VPA801(3),VPA802(2),VPA803(3), VPA804 (3),VPA 805(3), VPA816(3), VPA819 (1),VPA 820(1), VPA899(6).

Elective courses: VPA 812(2), VPA807 (2)

Clinical Veterinary Pathology Option

Core courses:VTC813(2),VPH815(2),VPH817(2),VPA801(3),VPA802(2),VPA806(2), VPA813 (3),VPA 814(3), VPA815(3), VPA816 (3),VPA 819(1), VPA820(1), VPA899 (6).

Elective courses: VPA808(2),VPA811(2)

Avian Pathology Option

Core courses:VTC813(2),VPH815(2),VPH817(2),VPA801(3),VPA802(2),VPA809(3), VPA814 (3),VPA 816(3), VPA817(2), VPA818 (2),VPA 819(1), VPA820(1), VPA899 (6).

Elective courses: VPA 811(2),VPA 810(3)