M.Sc. Physiology

Master of Science in Physiology

M.Sc. Physiology

1. List of Academic Staff

Name	Status and Qualification	Research Interest
Maryam T. Ayinla	Senior Lecturer & Ag. Head of Department, B.Sc., M.Sc., Ph.D. (Ilorin)	Endocrinology, Reproductive Physiology and Neurophysiology
B. V. Owoyele	Professor, B.Sc. (Ilorin); M.Sc. (Ibadan); Ph.D. (Ilorin)	Neurophysiology, Inflammation and Gastrointestinal Physiology
L. A. Olatunji	Professor, B.Sc. (Ilorin); M.Sc. (Lagos); Ph.D. (Ilorin)	Cardiovascular, Renal, Environmental and Molecular Physiology
L. A. Olayaki	Professor, MB;BS (ABU, Zaria); M.Sc. (Lagos); Ph.D. (Ilorin)	Endocrinology, Metabolism and Reproductive Physiology
T. M. Salman	Professor, B.Sc. (Ilorin); M.Sc., Ph.D. (Ibadan)	Endocrinology, Metabolism, Reproductive and Gastrointestinal Physiology
L. S. Ojulari	Senior Lecturer, MB;BS (Ilorin); M.Sc., Ph.D. (Lagos)	Endocrinology, Metabolism and Reproductive Physiology
T. O. Ayinde	Senior Lecturer, B.Sc., MB;BS (Ilorin); M.Sc. (Lagos); Ph.D. (IUA, Khartoum)	Neuroendocrine, Reproductive and Renal Physiology
A.O. Oyabambi	Senior Lecturer, B.Sc., MB;BS (Ilorin); M.Sc. (Lagos); Ph.D. (Ilorin)	Cardiovascular, Neuroendocrinology, Nutrition and metabolism
A. L. Oyewole	Lecturer I, B.Sc., M.Sc., Ph.D. (Ilorin)	Neurophysiology, Inflammation and Cell Membrane
Aminat O. Imamfulani- Hassan	Lecturer I, B.Sc., M.Sc., Ph.D. (Ilorin)	Neurophysiology and Metabolism
A. Amin	Lecturer I, B.Sc., M.Sc. (Ilorin); Ph.D. (NOVA, Lisbon)	Neuro-immunology, Metabolic diseases, Infectious diseases
W. I. Abdulmajeed	Lecturer I, B.Sc., M.Sc. (Ilorin); Ph.D. (NYMCTU, Taipei)	Cellular Neuroscience

M.M.B. Uthman

Reader , MB;BS, MPA, MPH (Ilorin); FWACP, MNIM (Chartered), MSM Cert. Data processing and Management Information System, Cert. Research Synthesis (Cape town); Cert. in Advanced Dip. In Ethics, (NIH, USA); Cert. EBHC (Stellenbosch)

Occupational Health, Demography, Research Ethics Evidence Based Health Care, Environmental Health, Statistics

* Lecturer from other Department

B. Introduction

The programme is designed for persons who wish to acquire deeper scientific knowledge in Physiology and to increase their capacity in teaching and research.

C. Philosophy

The philosophy of the programme is the development of highly skilled manpower for teaching, research and professional services for public, private and international organizations in the field of Basic Medical and Health Sciences.

D. Aim and Objectives

The aim of the programme is to enhance the theoretical and practical knowledge base of the students, and also to provide a solid foundation in the Physiological and Biomedical Sciences as a basis for teaching and research.

Objectives:

1. providing interested individuals with the necessary competencies and skills to function effectively as teachers, researchers and professionals in the health and medically related industry. This is with the view of providing students with the scientific knowledge and skills required to enhance their performance as members of the health care team in their various specialties and disciplines;
2. acquiring teaching, research and professional skills for imparting knowledge and service delivery in Nigeria and internationally;
3. producing competent and productive graduates who are capable of applying scientific knowledge and principles to solve human and environmental problems; and
4. producing scientists who are socially responsible and mindful of accepted norms and ethics.

E. Admission Requirements

Candidates are required to possess the following:

1. O‘ Level Credits passes or their equivalents in five subjects including Mathematics, Biology, Chemistry, Physics and English Language.
   1. A first degree in Physiology with a minimum of a Second Class Lower Division.
2. Candidates with MB;BS., B.D.S., DVM, BNS, B. Physiotherapy, OD or other relevant related disciplines. honours degrees in relevant specialties from recognised universities.

F. Duration of the Programme

1. The Full-time programme shall run for a minimum of 18 calendar months and a maximum of 24 calendar months.
2. The Part-time programme shall run for a minimum of 24 calendar months and a maximum of 36 calendar months.

G. Detailed Course Description

PHS 801 Respiratory System 2 Credits

Mechanics of respiration. Work of breathing. Surfactant. Pulmonary circulation and hypoxic pulmonary vasoconstriction. Gas exchange in the lungs and gas transport by blood. Foetalhaemoglobin. Chemical and neural control of respiration. Respiratory responses: exercise, altitude, deep sea diving, space travel. Artificial respiration. 15h (T); 45h (P); C

PHS 802 Cardiovascular System 2 Credits

Circulation of blood. Physiology of different vessels. Cardiac and vascular smooth muscle physiology. Receptor and calcium ion channels. Electrocardiogram. Cardiac output measurement and regulation. Control of arterial blood pressure. Physiology of vascular endothelium. Regional circulation. Responses to haemorrhage and exercise. Hypertension. 15h (T); 45h (P); C

PHS 803 Graduate Seminar 1 Credit

Selected topic in any area of Physiology but of interest to the student for literature review presented as a report after oral presentation. 45h (P); C

PHS 804 Endocrine Physiology 2 Credits

Mechanisms of hormone action. Determination of hormone levels bioassay. Second messenger and signaling systems. Protein kinases: IP3, G-Proteins. Hypothalamus- pituitary axis and hormonal actions of endocrine glands. Thyroid. Parathyroid. Adrenal cortex and medulla: renin angiotensin aldosterone system (RAAS). Pancreas. Pineal gland and diurnal rhythm. Prostaglandins. 15h (T); 45h (P); C

PHS 805 Renal Physiology 2 Credits

Clearance principle and determination of glomerular filtration rate and renal blood flow. Renal tubular secretion and reabsorption. Countercurrent principle and urine concentration mechanisms. Urea excretion. Tubular secretion of hydrogen ions and renal acid-base regulation. Osmoregulation. Hormones of the kidney. 15h (T); 45h (P); C

PHS 806 Reproduction 2 Credits

Gonads. Sex determination and differentiation. Male and female reproductive systems. Assessment of infertility. Hypothalamic: pituitary influence. Menstrual cycle. Pregnancy and lactation. Gonadal and placental hormones. Puberty and menopause. Foetal circulation. 15h (T); 45h (P); C

PHS 807 General Physiology 2 Credits

Cell structure and functions. Genes and DNA. Membrane physiology. Transport of substances across membranes and bioelectric potentials. Free radicals. Ageing. 15h (T); 45h (P); C

PHS 808 Instrumentation/Research Methodology 2 Credits

Principles of electronics and integrated circuits. Calibration of equipment reliability, sensitivity and reproducibility. Fault detection and trouble shooting. Basic measuring. ICT methods and use. Literature search. Design of experiments, Methods of data collection. Handling of laboratory animals. Ethical clearance in human studies and laboratory animals. 15h (T); 45h (P); C

PHS 809 Gastrointestinal System 2 Credits

Gastrointestinal motility. Mechanisms of deglutition. Composition of GIT, secretions, functions and control. Liver and bile. Digestion and absorption of carbohydrates, fats and proteins. Absorption of water and ions. Gastrointestinal hormones. Methods of study of gastrointestinal functions. 15h (T); 45h (P); C

PHS 810 Neurophysiology 3 Credits

Nerve and muscle physiology. Biologic potentials. Nerve impulse. Nerve types and classification. Neuromuscular transmission. Sarcotubular system of muscle. Muscle contraction. CNS. Sensory receptors. Synaptic transmission. Spinal reflexes. Thalamic nuclei. Cerebral cortex. Spinal tracts. Basal ganglia. RAS. Imaging techniques. Evoked potentials. Cerebellum functions. Higher functions of the brain and Electroencephalogram (EEG). ANS. Neurotransmitters. Special senses. 30h (T); 45h (P); C

PHS 811 Blood and Body Fluids 2 Credits

Body fluids and compartments. Methods of determination of body fluids. Major cations and anions in body fluids. Solutions. Blood components: cellular, plasma, functions. Clotting of blood. Basic concepts of immunity. Humoral and cell-mediated immunoglobulin. 15h (T); 45h (P); C

PHS 812 Nutrition and Metabolism 2 Credits

Aims of nutrition. Energy content of food: carbohydrates, proteins, fats, basal metabolic rate. Calorie requirements per day. Estimation of obesity: body mass index. Vitamins and mineral requirements and functions. 15h (T); 45h (P); E

PHS 813 Environmental Physiology 2 Credits

Responses to thermal changes. Regulatory responses to pollutants. Responses to toxic waste. Acid rain. Ozone layer. Systemic effects of environmental pollution. Industrial waste. Responses to climate change. 15h (T); 45h (P); E

PHS 814 Biotechnology 2 Credits

Genetics and genomics. Membrane structure and genetic control. Cellular messengers. Stem cell research. Knockout and transgenic mice. Recombinant DNA. Polymerase Chain Reaction (PCR). Northern Blot. Western Blot techniques. Human genetic project/genome. Nanotechnology and targeted drug delivery. 15h (T); 45h (P); E

PHS 815 Pharmacologic Techniques 2 Credits

Techniques applied in pharmacological activities and mechanisms. 15h (T); 45h (P); E

PHS 839 Dissertation 6 Credits

Research on the candidate‘s area of interest presented in a dissertation. The dissertation would be examined orally before panel of examiners. 270h (P); C

ECH 842   Introduction to Medical Statistics 2 Credits

Use of statistics and sources of data. Collection, Organisation and Summarisation of data. Basic probability concepts. Probability distribution. Sampling distributions. Estimation techniques. Hypothesis testing. 30h (T); C

• Graduation Requirements

To be awarded the degree, a candidate must have passed a minimum of 34 Credits comprising all core courses and any 2 Electives.

I. Summary

Core Courses: PHS 801 (2), PHS 802 (2), PHS 803 (1), PHS 804 (2), PHS 805 (2),

PHS 806 (2), PHS 807 (2), PHS 808 (2), PHS 809 (2), PHS 810 (3), PHS 811 (2),

PHS 839 (6), ECH 842 (2)  30 Credits

Elective Courses: PHS 812 (2), PHS 813 (2), PHS 814 (2), PHS 815 (2)   8 Credits