M.Sc. Medical Microbiology and Parasitology

Master in Medical Microbiology and Parasitology

M.Sc. Medical Microbiology and Parasitology

1. List of Academic Staff

Names	Status and Qualification	Research Interest
A. Fadeyi	Professor, Head of Department. B.Sc., M.Sc., MB;BS (Ilorin); FMCPath. (Nigeria)	Hospital Acquired Infections, Anti- Microbial Resistance. Molecular Microbiology and Malariology
C. Nwabuisi	Professor, MB;BS, M.Sc. (Lagos); FMC Path. (Nigeria)	Cryptosporidiosis, Chemotherapy of infections, Infectious Diarrhoea, Sexually Transmitted Diseases and Anaerobic Infections.
A.A. Akanbi II	Professor, MB;BS (Ilorin); FMCPath. (Nigeria)	Enteric Bacterial Infections and Antimicrobial Therapy in Infections. Enteric Parasitic Infections.
A. Nyamngee	Senior Lecturer, B.Sc. (Jos); M.Sc., Ph.D. (Ilorin)	Public Health Parasitology, Protozoology, Helminthology and Medical Statistics.
M. K. Sulaiman	Lecturer II, B.Sc. (KUL, UK); M.Sc. (UU, UK); Ph.D. (UNIS, Guilford)	Virus Diseases Surveillance and Epidemiology, Virus-Host Relationships
L. D. Edungbola	Professor, B.Sc.(OAU, Ile-Ife); Ph.D. (The John Hopkins)	Epidemiology and Contol of Neglected Tropical Diseases, the assessement of Endemic Health Problems among th3e underdeveloped and neglected rural population

B. Introduction

The teaching of Medical Microbiology and Parasitology to medical and postgraduate students has been a composite part of this department since inception. The postgraduate component of this programme is made up of four different units, viz Bacteriology, Parasitology, Virology and Mycology leading to the award of M.Sc. and Ph.D. degrees. Over the years, the department has raised needed manpower through its postgraduate programme, in line with the philosophy of the University at large and the faculty of basic medical sciences in particular. To accommodate the progress in postgraduate studies, the M.Phil. program has been added.

C. Philosophy

The philosophy is to produce Master graduates that are highly skilled enough to serve as manpower source for teaching, research and professional services for the public, private and international organizations in the field of medical microbiology and parasitology.

D. Aim and Objectives

The objectives of the Masters, M.Phil, and Ph.D. degree programmes in Medical Microbiology and Parasitology are:

1. Providing interested individuals with the necessary competencies and skills to function effectively as teachers, researchers and professionals in the health and medically related industry. This is with the view of providing students with the scientific knowledge and skills required to enhance their performance as members of the health care team in their various specialties and discipline.
   1. Acquisition of teaching, research and professional skills for imparting knowledge and service delivery in Nigeria and internationally.
   1. Producing graduates who are capable of applying scientific knowledge and principles to solve human and environmental problems.
   1. To produce scientists who are socially responsible and mindful of accepted norms and ethics.

E. Admission Requirement

1. All candidates must fulfil the matriculation requirements as stipulated by the programme of the university and as specified by the undergraduate BMAS.
   1. Candidates must possess bachelor‘s degree from a recognized university and must obtain a minimum of second class lower division in their fields or related disciplines.
   1. Candidates with M.B.B.S, B.DS, DVM, BNS, B.PHYSIOTHERAPY, OD or other unclassified honours degrees in relevant specialties from recognized universities are also eligible.
   1. Candidates with HND or other equivalent qualifications e.g. ALLMS could be considered for admission provided they have obtained a postgraduate diploma at credit level in related disciplines.
   1. On completion of the M.Sc. programme candidates who obtained weighted score of at least 60% (CGPA of 3.5/5.0) are eligible to proceed to Ph.D. programme in Medical Microbiology and Parasitology, Candidates who obtained a weight score between of 55% and 59% (CGPA of 3.0 -3.49) would be eligible for M.Phil/Ph.D programme. However candidates who obtained weighted score between 50% and 54% (CGPA of 2.5 -2.99) shall be eligible to proceed to M.Phil. programme in Medical Microbiology and Parasitology

F. Duration of Programmes

1. A full time Master‘s Programme shall run for a minimum of 18 calendar months and a maximum of 24 months.
2. Part-time masters‘ programmes shall run for a minimum of 30 calendar months semesters and a maximum of 48 calendar months.
3. For extension beyond the specified maximum period, a special permission of the Board Postgraduate School shall be required on the recommendation of the department.

G. Detailed course description

MIP 801 General Medical Microbiology 2 Credits

History of Microbiology; general properties of microorganisms; taxonomy and nomenclature; structural characteristics of microorganisms; culture media and culture techniques; biochemical disinfection; Kinetics of microbial killing; bacterial pathogen city; toxicology and food poisoning. 30h (T); C

MIP 802 Microbial Physiology 2 Credits

Biological Macromolecules; amino acids, sugars, nitrogenous bases, Protein synthesis-transcription and translation. Enzymes and coenzymes in metabolism, Pathways of microbial metabolism, basis for Entero-bacteriaceae differentiation, Energy generation, Bacterial growth; iron and oxygen requirements, Gene expression, Regulation of gene expression. 30h (T); C

MIP 803 Immunology and Immunity to Infection 2 Credits

Cells of the Immune system; ontogeny and phylogeny of immune response; synthesis of antibodies; antibody specificity and avidity; humoral immunity (B-cell mediated); cell- mediated immunity; transplantation immunology; auto- immunity and auto-immune diseases; vaccines. 30h (T); E

MIP 804 Clinical and Diagnostic Microbiology 2 Credits

Design of Microbiology Laboratory. Biologic basis of human infections. Collection, handling, transportation and processing of specimens for laboratory diagnosis of human infections virulence factors; acute and chronic infections, nosocomial infections; infections in the immune-compromised. Bacterial and viral zoonoses. Vaccines. 30h (T); 45 (P); C

MIP 805 Anaerobic Bacteriology 2 Credits

Anaerobiosis; gram-positive and gram-negative non-spore forming anaerobic bacilli; gram-positive and, gram-negative anaerobic cocci; gram-positive spore-forming anaerobes, laboratory diagnosis, chemotherapy and clinical significance of anaerobic infections. 30h (T); C

MIP 806 Medical Mycology 2 Credits

Classification of fungi. Structural characteristics of fungi. Morphologic basis of fungal identification. Fungal sexual and asexual reproduction. Fungi imperfecti, Fungal epidemiology; Fungal infections of man and domestic animals. Superficial mycoses, deep and systematic mycosis, Filamentous fungi ; Fungal infection in the immune-compromised. 30h (T); C

MIP 807 Graduate Seminar 1 Credit

Credits — to be arranged. Each student shall deliver a minimum of four seminars on current topics in Microbiology and Parasitology approved by the Head of Department, Papers in form of written essays of ten pages shall accompany each presentation. 15h (T); C

ECH 842 Introduction to Medical Statistics 2 Credits

Detail course content as prescribed under Department of Epidemiology and Community Health. 30h (T); C

MIP 809 Mycobacteriosis 1 Credit

Mycobacterium tuberculosis complex, Atypical Mycobacteria, Mycobacterium leprae

Epidemiology of Mycobacteria, cultivation, antimicrobial sensitivity testing and chemotherapy of mycobacteria. 15h (T); C

MIP 810 Advanced Virology 2 Credits

Genome Organization of Selected Viruses. Viral Receptors. Role of Ecology in the Emergence and Re-emergence of Viruses. Viral Adaptations. Evolution of Viruses. Viral Zoonoses – Viral Hemorrhagic Fevers. Viruses as Tools in Vaccine Technology. Evolution of Retroviruses. Tumor Virology. Virus Isolation Techniques. 30h (T); E

MIP 811 Animal Cell Culture 2 Credits

Cell Structure. Cell physiology. Types of cells in viral culture. Cell culture media. Cell culture types- monolayer and suspension. Cell culture properties- biochemical markers; karyotyping of cultured cells and genetic mapping. Cell cycle phase manipulation and premature chromosome condensation techniques. 15h (T); 45h (P); C

MIP 812 General Medical Parasitology 2 Credits

Principles and concepts of Medical Parasitology and entomology; technical Terms, definitions and classification; parasite life-cycle and diagnosis using selected Direct and Indirect examples; Damages caused by parasites; WHO-TDR/NTDS, Burden of parasitic diseases and the challenges of their control and eradication. 30h (T); C

MIP 813 Mycoplasmatology and Chlamydiology 1 Credit

The course shall cover the structure; metabolism, laboratory isolation, identification and epidemiology of Mycoplasma and Chlamydia, clinical spectrum of infections. 15h (T); E

MIP 814 Antimicrobial Agents Chemotherapy 2 Credits

History of antimicrobial agents; properties of important chemotherapeutic agents and antibiotics; structure activity relationships; antimicrobial therapy of tropical infectious diseases; susceptibility determinations; drug levels; mechanisms of microbial resistance to drugs. 30h (T); C

MIP 815 Diagnostic Clinical / Medical Parasitology 3 credits

The usefulness and significance of diagnosis in medical and clinical Parasitology, sources of materials for diagnosis, procedures for specimen collection, preservation, culturing, concentration and staining for examination of Stools, Urine, Sputum, CSF, Blood, Skin, Xenodiagnostic, Sero- diagnostic and Immuno-diagnostic methods. 30h (T); 45h (P); R

MIP 816 Epidemiology of Infection Diseases 1 Credit

Epidemiology and geographical distribution of major bacterial, viral, fungal, protozoan, metazoan and arthropods diseases in relation to infectious agents, susceptibility, Resistance, mode of transmission, environmental factors, Reservoir host, prevalence, incidence, surveillance, prevention, treatment, Control, eradication and devolution. 15h (T); E

MIP 817 Research Methodology 3 Credits

Fundamental basis of systematic approaches to the design and execution of multi-purpose research project. Principles of reasoning in the development of research objectives, design of reproducible methodology; execution of projects and handling of constraints on execution. Budget and ethical issues. 45h (T); C

MIP 818 Parasites and Parasitism 2 Credits

The triad of relationship between the Parasite, the Host and the Environment; the Evolution of Parasitism and parasites; Animal Association and Significance; Distribution, Varieties and Life- cycles of Parasites. Adaptation to Parasitism; Types of Host and Parasite Relationship; Susceptibility, Resistance, Immunity. 30h (T); E

MIP 819 Medical Entomology & Vector Control 2 Credits

Introduction to Medically Important Arthropods; Characteristics and Grouping of Arthropods; Medical and Public Health Importance of Arthropods; including insects, Ticks, Mites, Lice, Fleas, Myiasis, Disease Transmissions; Venoms, Defense Secretions and Allergens; Principles of Vector Control. 15h (T); 45h (P); R

MIP 820 Tropical Ecology and Human Health 2 Credits

Inter-relationship between human ecology, human behaviours, and diseases arthropods, vectors and transmission e.g. Schistosomiasis and its association with Dams, water contact and irrigation; deforestation; natural disaster; climatic change, Global warming, population aggregation; Environmental manipulation, etc. 30h (T); E.

MIP 821 Advanced Medical Protozoology. 2 Credits

Classification, Developmental biology, Epidemiology, Treatment, Control/ Eradication of Medically Important Protozoan        Diseases including: Malaria; Amoebiasis; Trichimoniasis; Giardiasis; Trypanosomiasis; Toxoplasmosis, Leishmaniasis; Cryptosporidiasis and Microsporidiasis. 30h (T); C

MIP 822 Advances in Parasitology 3 Credits

Contemporary Topics (e.g TDR and NTDs,) in Parasitology, and Parasite Control/ Eradication e.g., Drug and Vaccine Developments, Use of Parasites, Predators, Plants and other Biological and Non- biological materials for Intervention; Merits and Limitations of Vaccines and Chemotherapy in the Control of Tropical Diseases. 45h (T); E

MIP 823 Advanced Medical Helminthology 2 Credits

Classification, life-cycle, Epidemiology, Treatment, Control and Eradication of Medically important Helminthiasis including; Intestinal Helminthiasis, Filariasis (plus Onchocerciasis), Dracunculiasis, Trichinosis,. Taeniasis, Echinococcosis, Dibothriocephalosis; Paragonimiasis, Schistosomiasis; Fascioliasis; Clonorchiasis. 30h (T); C

MIP 824 Microbial Genetics 3 Credits

The Microbial genome. Chemistry of DNA and RNA; Information transfer among microbes; Mechanisms of gene alterations and mutations: transposable elements and gene movements in Microbes, mechanisms of gene transfer and antibiotic resistance restriction fragment polymorphism in the study of microbial genes; genetic mapping. 45h (T); E

MIP 825 Biomedical Writing 1 Credits

Basic elements of scientific writing; structure and organization of thought in writing, annotations, referencing and use of defective constructions as illustrations in practical writing exercises. 15h (T); C

MIP 826 Research Project 5 Credits

Original research project conducted on an approved topics. 225h (P); C

• Graduation Requirement

To be awarded a Master‘s degree candidate must pass a minimum of 30 credit Units made up as follows:

1. Core courses on minimum 18 credit units.
2. Required/Elective courses of minimum 6 credits units
3. Dissertation 6 credit units.

I. Summary

1. Bacteriology Option.

Compulsory Courses: MIP 804(3), 807 (1), 815 (3), 817 (3), 826 (5), 825 (1) = 16 Credits.

Required Courses: MIP 801 (2), 802 (2), 803 (2), 805 (2), 808 (2), 809 (1), 814(2), 816(1) 824 (3)=

17 Credits

Elective/Required Courses: MIP 813 (1) = 1 Credits Total: C + E =34 Credits.

II.  Medical Parasitology Option.

Compulsory Courses: MIP 804 (3), 807 (1), 815 (3), 817 (3), 826 (5), 821 (2), 823 (2), 825 (1)= 20

Credits

Required Course: MIP 801 (2), 803 (2), 808 (2), 812 (2), 816 (1), 819 (2) = 11 Credits

Elective Courses: MIP 818 (2), 820 (2), 822 (2)=6 Credits Total: C+E=35 Credits.

III.  Medical Virology Option.

Compulsory Courses: MIP 804 (3), 807 (1), 810 (2), 811(2), 815(3), 817 (3), 826 (5), 825 (1)= 20

Credits.

Required Courses: MIP 801 (2), 802 (2), 803 (2), 808 (2), 813(1), 814 (2), 816 (1), 824(3)= 15

Credits

Total: C +E Courses =35 Credits.

IV.  Medical Mycology option.

Compulsory Courses: MIP 804 (2), 806 (2), 807 (1), 815 (3), 817 (3), 826 (5), 825 (1) = 18 Credits.

Required Courses: MIP 802 (2), 803 (2), 808 (2), 809 (1), 814(2), 816(1), 824(3) = 13 Credits

Elective Courses:

Total: C +E Courses =31 Credits.